Expedition into the genome of Saprolegnia parasitica: searching for the foundation of heightened pathogenicity

Saprolegniosis, the most frequent disease in wild fish, has reemerged as principal cause of fish kills. ​

Saprolegnia parasitica, the most virulent facultative pathogen responsible for saprolegniosis, remains under-investigated. Genetic factors and mechanisms underlying variable pathogenicity of the microbe are not yet known.

Project aims:

  • Sequence the genomes of Norwegian S. parasitica isolates
  • Develop an analytical pipeline for the whole-genome sequencing (WGS) of Eukaryotes​
  • Uncover the genetic factors responsible for S. parasitica​ pathogenicity

Funding: Norwegian Veterinary Institute

Project periode: 2023–2025