Navigating the threat of azole resistance development in human, plant and animal pathogens in Norway
Background: Fungal infections caused by opportunistic fungi such as Aspergillus fumigatus kill more than 1.5 million people annually worldwide (equivalent to deaths caused by tuberculosis or malaria). The number will likely increase considerably because resistance against azoles is dispersed globally at a disturbing speed. The global community has a strong focus on antimicrobial resistance (AMR), but almost solely from the bacterial perspective. The Navazole project focuses on a neglected part of the One Health AMR resistance perspective and addresses both mechanisms of AMR and strategies to prevent AMR in fungal pathogens.
Goal: The overall aims are to explore how fungi develop resistance to fungicides and to identify and understand Norwegian conditions where the risk of resistance development is particularly high.
Collaboration project with Norwegian food producing enterprises (2021–2026)