Christiane Kruse Fæste, Dr. rer. nat.

Toxinology Research Group
Norwegian Veterinary Institute
Elizabeth Stephansens vei 1
1433 Ås


Research interests

Xenobiotic metabolism and toxicokinetics including determination of biotransformation pathways, inhibition and interaction studies, and prediction of human exposure.
Risk assessment regarding exposure of humans and domestic animals from contaminated food and novel food proteins.
Characterisation of biomarkers for presence and effects of contaminants and diseases by proteomic and biochemical analysis.
Identification of food allergens and elucidation of allergenic potentials using immunochemical and spectrometric methods.
Member of the Norwegian Committee for Food Safety (Feed Panel), CEN (TC275 WG12 Food Allergens) and AOAC (Food Allergen Community).


Studies in chemistry and biochemistry at the Technical University Hanover/Germany (TUH) and the Medical School Hanover/Germany. Master in pharmacology and biochemistry. Doctoral studies at the Max-Planck-Institute for Plant Breeding in Cologne/Germany and degree from the TUH in biochemistry. Laboratory leader in preclinical pharmacokinetics at Bayer Healthcare AG in Wuppertal/Germany. Senior scientist at the Norwegian Veterinary Institute since 2002.


Ongoing projects

CRC-3p – Processed foods and colorectal cancer: Effect of protein source, processing and dietary patterns
MoksiMark – is moxidectin suitable for the treatment of brainworm (Elaphostrongylus rangiferi) infections in reindeer?
ShellFeed – Risk assessment of algal toxins in new marine feed sources for salmon
GyroOmics – Multi-Omics analysis for the differentiation of salmon fluke (Gyrodactylus salaris) susceptibility in Atlantic and Baltic salmon (Salmo salar)
DetoxBug – Biotransforming mycotoxin-contaminated raw materials into valuable feed sources by detoxification in insect larvae
GreenBait – Progress toward environmentally safer rodenticides
CARDIO POX – Assessment of biomarkers in viral cardiorespiratory diseases in Atlantic salmon
PARC – European partnership for the assessment of risks from chemicals

Recent projects

MetAct – Biomarkers of exposure to azoxymethane in intestine and liver of A/J APCMin/+ mice
Slimy – Host immunity and skin microbiome interplay: Importance for protection against sea lice infestation in Atlantic salmon
CerveauMoisi – Strengthened French-Norwegian connection to uncover the neurotoxic potential of natural toxins
CiguaPIRE – Advancing global strategies and understanding on the origin of ciguatera fish poisoning in tropical oceans
iNOBox – A Technology- and Market-driven Innovation e-Toolbox towards a Sustainable, Competitive and Science-based Agri-Food Industry in Norway
ISAbreed – ISA resistance in Atlantic salmon: Defining new phenotypes for accurate breeding
Gillmodel – Development of an in vitro model to study environmental factors influencing the gill epithelial function
BioDirect – Biomarkers and Bioassays for Animal and Fish Research and Diagnostics
MycoSafeSouth – European–African partnership for safe and efficient use of mycotoxin-mitigation strategies in sub-Saharan Africa
SafeFish – Implications of green Fish feed for consumer safety – carry-over of plant peptides, natural toxins and bioactive compounds (NFR Havbruk2)
DONNER – Deoxynivalenol (DON) – Nervous effects reconnaissance
Gyrochloramine – Chloramine treatment of watercourses for the control of Gyrodactylus salaris infestation
ReinBrain – Parasites in the brain – a climate problem for reindeer
NewMHCI – Changing our view on major histocompatibility complex (MHC) class I in vertebrates
PromoFish – Establishment of salmon skin mucus multi-omics analyses
FunTox – Fungi and mycotoxins in a «One Health» perspective
MycoPig – Mycotoxins and toxigenic fungi in Norwegian pig farming: consequences for animal health and possible intervention strategies
MycoFish – Contaminants, nutrients and health challenges in the novel production of farmed Atlantic salmon
Food Allergen Methods – Development of a coordinated research program for food allergens – identification, modification and in vivo responses
LCMSMS for Food Allergens – The development of a project proposal on LCMSMS for the determination of low levels of food allergens
Anisakis simplex – Development of tools for product control and human risk evaluation in fishery value chains (Anisakis simplex)


Book chapters

  • Fæste CK: Allergens in Peanut, Soybean, and Lupin, Chapter 3, Food Allergens: Analysis Instrumentation and Methods, edt. Nollet L. Van Hengel A. Taylor & Francis Group, LLC, Boca Raton, Fl. USA, 2011.
  • Fæste CK: Fish allergen detection, Chapter 21, Molecular Biological and Immunological Techniques and Applications for Food Chemists, edt. Popping B, Diaz-Amigo C, Hoenicke K.  John Wiley & Sons, Ltd, 2009.
  • Fæste CK: Lupin allergen detection, Chapter 22, Molecular Biological and Immunological Techniques and Applications for Food Chemists, edt. Popping B, Diaz-Amigo C, Hoenicke K.  John Wiley & Sons, Ltd, 2009.