Deoxynivalenol – nervous effects reconnaissance
August 1, 2018Data on neurotoxicological effects of the mycotoxin deoxynivalenol (DON), also called vomitoxin, are limited. Orally exposed laboratory (mice, rats) and domestic animals (pig, chicken) show behavioural changes such as feed refusal, increased locomotor activity and aggressive behaviour, and DON plasma concentrations at ppm-level result in vomiting in pigs and humans. Preliminary observations suggest that DON…