Using boric acid gel for extraction of azaspiracids
June 26, 2018Azaspiracids (AZAs) are marine algal toxins that can cause food poisoning in humans. Azaspiracids belong to a family of more than 50 polyether toxins originating from marine dinoflagellates such as Azadinium spinosum. Figure 1: Structure of azaspiracid-1 Boric acid gel can bind selectively to compounds containing vic-diols or α-hydroxycarboxylic acids via formation of reversible boronate…
Is P-glycoprotein involved in toxicity of deoxynivalenol?
June 26, 20184-Deoxynivalenol (DON) is the most prevalent Fusarium mycotoxin, and it frequently occurs in grains such as wheat, barley, oats and rye all over the world. The ingestion of DON contaminated feed has been shown to result in pro-inflammatory effects as well as various pathological lesions, including the necrosis of the intestinal epithelium in several animal…